RESP 106 - Cardiopulmonary Pharmacology

1. Evaluate data in the patient record (e.g., patient history of present illness (HPI), orders, medication reconciliation, progress notes, DNR status/advanced directives, social/family/medical hx, and patient’s pathophysiological state)
2. Evaluate lab data (CBC, electrolytes, coagulation, C&S, sputum, cardiac biomarkers
3. Perform clinical assessment by interviewing patient to assess:
   1. Level of consciousness and orientation, emotional state, and ability to cooperate
   2. Shortness of breath, sputum production, and exercise tolerance (such as exercise induced asthma)
   3. Activities of daily living
4. Perform clinical assessment by inspection to assess cough, sputum amount and character
5. Perform clinical assessment to assess breath sounds
6. Discuss administration of SVN, MDI/SMI, DPI, and valved holding chambers:
   1. Infection control
   2. Assembling/troubleshooting of equipment
   3. Determine which modality is most appropriate for age specific
   4. Determine which modality is most appropriate for clinical presentation
7. Ensure modifications of respiratory care plan for:
   1. Adverse or life threatening events
   2. Starting treatment based on patient response
   3. Discontinuing treatment based on patient response
8. Ensure modifications of respiratory care plan by recommending and implementing treatments based on patient response and national guidelines (ARDS Net, NAEPP, and GOLD) for selective diseases
9. Administer medications and specialty gases to ensure modifications are made to the respiratory care plan to include indications, contraindications, hazards, mode of action, classes/subclasses, concentration, doses, names (generic/brand) and frequencies:
   1. Bronchodilators (Albuterol, Levalbuterol, Salmeterol, Formoterol, Arformoterol, Ipratropium bromide, Tiotropium bromide, Methylxanthines)
   2. Corticosteroids (Fluticasone, Beclomethasone, Budesonide, Flunisolide, Triamcinolone, Prednisone, Methylprednisolone)
   3. Combining Medications (Combivent, Duoneb, Advair, Symbicort)
   4. Mucolytics (Acetylcysteine, Sodium Bicarbonate, Recombinant Human DNAse)
   5. Pulmonary Vasodilators (Prostacyclins: Epoprostenol, IIoprost, Sildenafil, INO)
   6. Wetting Agents Saline solutions (0.45%, 0.9%, 1.8-15%)
   7. Leukotriene Modifiers (Montelukast, Zafirlukast, Zileuton)
   8. Mast Cell Stabilizers (Cromolyn sodium)
   9. Mucosal Vasoconstrictors/Decongestants (aerosolized racemic epinephrine)
   10. Inotropic Agents (Digitalis, Digoxin)
   11. Anti-arrhythmic Agents (Amiodarone, Procainamide, Verapamil, Lidocaine, Atropine, Epinephrine)
   12. Antianginal Agents (Nitroglycerin)
   13. Vasodilator Drugs (Nitroprusside, Milrinone)
   14. Vasoconstrictor/Vasopressor Drugs (Epinephrine, Norepinephrine, Dopamine, Dobutamine)
   15. Diuretics (Furosemide, Mannitol, Acetazolamide)
   16. Neuromuscular Blocking and Reversal Agents (Succinylcholine, Neostigmine, Pancuronium, Vecuronium, Atracurium, Cisatracurium, Rocuronium)
   17. Sedatives (Alprazolam, Diazepam, Midazolam, Lorazepam)
   18. Anesthetics (Propofol, Ketamine)
   19. Analgesics (Morphine, Codeine, Meperidine, Fentanyl, Hydromorphone, Oxycodone, Hydrocodone)
   20. Surfactant Replacement Therapy (Calfactant, Beractant, Poractant alfa, Lucinactant)
   21. Antimicrobial agents - inhaled and systemic - (Ampicillin, Amoxicillin, Nafcillin, Cephalexin, Cefazolin, Cefaclor, Cefoxitin, Ceftriaxone, Cefepime, Amikacin, Gentamicin, Tobramycin, Vancomycin, Erythromycin, Azithromycin, Isoniazid, Rifampin, Ethambutol, Streptomycin, Cycloserine, Ethionamide)
   22. Antiviral Agent (Ribavirin)
   23. Anti-pneumocystis Agent (Pentamidine)
   24. Vaccines (Respiratory Syncytial Virus Immune Globulin Intravenous, Palivizumab)
   25. Biologics for asthma (e.g. Dupixent)
   26. CFTR modulators (e.g., Trikafta)

• • Pulmonary vasodilators (e.g., Epoprostenol)
  • Nebulized antifibrinolytics and anticoagulants

 

COURSE CONTENT: Topical areas of study include -  

• Pharmacokinetics / Pharmacodynamics
• Dosage calculations
• Peripheral nervous system agents (Cholinergic, Nicotinic, Muscarinic)
• Respiratory treatments (Antihistamine, Adrenergic, Xanthines, Stimulants)
• Glucocorticoids
• Mucolytic agents
• Antibacterial medications
• Antiviral and antifungal agents
• Cardiovascular agents (Cardiotonics, Antianginals, Antiarrhythmics, Antihypertensive)
• Diuretics
• Psycho hypnotic
• Analgesic
• Anesthetics
• Evaluations

 
GRADING POLICY

          A        92-100   

          B        85-91    

          C        78-84 

          D        76-77     

          F        <76 (A grade of 75.9999% will not be rounded to a passing grade)   

 
Course Addendum - Syllabus (Click to expand)