May 03, 2024  
2022-2023 Catalog 
    
2022-2023 Catalog [ARCHIVED CATALOG]

BIOL 221 - Molecular Biology


PREREQUISITES: CHEM 105 - General Chemistry I  and BIOL 121 - General Biology I  or BIOL 105 - Biology I - Molecular and Cellular Processes  
PROGRAM: Life Sciences
CREDIT HOURS MIN: 4
LECTURE HOURS MIN: 2
LAB HOURS MIN: 4
DATE OF LAST REVISION: Fall, 2018

This course will introduce DNA, RNA and proteins and review their structures and functions, including their physical and chemical properties and their roles in cellular metabolism. The course will include an in-depth look at the synthesis of these molecules, as well as DNA replication, transcription and translation.

MAJOR COURSE LEARNING OBJECTIVES: Upon successful completion of this course the student will be expected to:

  1. Describe the physical structure and functions of the major biological macromolecules and how they are related.
  2. Understand the roles of DNA, RNA and proteins in cellular metabolism.
  3. Recognize how the macromolecules are made.
  4. Identify the processes of synthesis and replication for each of these molecules.
  5. Understand transcription and translation and their relationship with the molecules.
  6. Know how the processes of synthesis, replication, transcription and translation are controlled and the effect DNA mutagenesis has on these processes.
  7. Understand and contrast gene regulation in prokaryotes and eukaryotes.
  8. Identify and understand the role protein modification, such as proteolytic cleavage, phosphorylation, dephosphorylation, ubiquitination and glycosylation has on protein structure and function.
  9. Describe the technologies used in exploration of these molecules.
  10. Understand and describe the historical and current issues in molecular biology relevant to society.
  11. Describe different model systems and how they are used to study molecular biology.
  12. Develop laboratory skills related to molecular biology in order to record and make accurate observations and measurements.
  13. Collect, analyze, and present scientific data graphically and orally using appropriate scientific language.
  14. Identify and evaluate reliable primary scientific sources; be able to write literature reviews and scientific lab reports and present scientific information orally.


COURSE CONTENT: Topical areas of study include -  

  • DNA, RNA and protein structures and functions
  • DNA mutagenesis
  • Gene expression controls
  • Model systems in molecular biology
  • Molecular biotechnology
  • Prokaryotic and eukaryotic gene regulation
  • Protein Modification
  • Replication of macromolecules
  • Role of macromolecules in cellular metabolism
  • Synthesis of macromolecules
  • Society issues related to molecular biology
  • Transcription
  • Translation

 
Course Addendum - Syllabus (Click to expand)